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Definitions by MAC L.

Hit-Em-Up 

Murder verbally or physically. Used by 2-pac or Lil Weezy(Lil`Wayne). A killing. Used to threaten a group of people.
Nigga I HIT-EM-UP. He hit-em-up. Imma hit-em-up
Hit-Em-Up by MAC L. June 2, 2007