A sporadic, random and unintended remark discharged orally as a result of the mind's need to facilitate a release of bottled up thoughts.
Her proclamation was a mindfart and made no sense whatsoever.
An infectious disease spread by direct or indirect contact with a loser or a group of losers. Symptoms may vary and include lack of motivation, laziness, vomitting, lack of interest in anything sexually stimulating, low self-confidence, inferiority complex, antisocial behavior, anxiety...
Oh no, you've got loseritis.