1 definition by Juice*

1. It’s a disease that infects woman who often dress conservative and act perfectly normal during the day. When infected, they choose to dress more provacative. They always act a bit more naughty then usual during a night out with girls.

2. A sexy, naughty, bitchy version of the girl next door that typically comes out at night to play.
"We got that skankitis! And we don't take no vaccines, we just take shots!"
by Juice* January 29, 2009
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