2 definitions by Iguywhoknowsjames

Typically someone who is either adopted, always disappointing someone or was an unwanted pregnancy. Typically has more than two more siblings. He usually is born with a mental disorder.
Did you hear Mrs. Martin called James a mistake today?
by Iguywhoknowsjames September 27, 2019
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This is a chain-reaction of thot/hoe personalities and actions spreading to more people from one person. If someone is a thot /hoe they might start the Lopez Effect which will end up with a greater thot/hoe population. The Lopez Effect was named by Marshall Lopez who studied females put into different scenarios, and each female was different when it came to personalities. His experiment started with one thot/hoe and six other girls, but by the end of week six of the seven became thots/hoes. The science behind it is that the drama a thot/hoe will deal with will spread onto others which makes them a thot/hoe over time. Popular areas of the Lopez Effect are high schools, colleges/universities, modeling, celebrities, and lesbian sex.
Cole: Yo, you know that girl Angelina?
James: Yeah, what about her?
Cole: I think the Lopez Effect is taking place she used to be a nerd but now she a HELLA thot!
James: U right bih
by Iguywhoknowsjames November 6, 2019
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