Simply means "way of the road". This phrase was popularized by Twitch streamer TimtheTatMan. When something unfortunate would happen, he'd simply say "that's the way of the road".
WOTR: Way of the road
*Ninja gets killed by bots* Tim: "Way of the road, bud"
Nick: "Why'd you take fall damage?"
Tim: *gets close to microphone* "Cause its the way of the road"