2 definitions by Cap'n Hook
The act of eating way to much pizza and reaching a point of regret in which throwing up feels imminent. Pizza cancer is often achieved at a pizza buffet with extra greasy pizza.
Guy 1: What's wrong with Bill he looks like he's about to die?
Guy 2: He's fine he just got pizza cancer at lunch.
Guy 2: He's fine he just got pizza cancer at lunch.
by Cap'n Hook December 31, 2013
by Cap'n Hook February 18, 2008