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ligand substitution 

The act of replacing a ligand in a complex ion. This results in a change of colour of the complex ionic solution.
Rasta: What does ligand substitution do?
Me: Ligand substitution results in a different coloured solution!
ligand substitution by TheWizoid November 13, 2016

A "Greg Scott" Substitution 

Whilst playing Fifa online, pretending to make a substitution then quitting due to being one or more goals behind.
I was beating him 1-0 with 5 minutes left to go and he made "A "Greg Scott" Substitution"

substitution 

5 foot Jen is paying for her college through substitution.
substitution by Lori-Ann January 29, 2008

pillow substitution 

The act of switching pillow faces when a pillow becomes too warm due to absorption of the sleeper's body heat. This act can be accomplished by turning the pillow over, revealing the unused and cool side, or by getting a new pillow.
Last night I was pretty hot after doing my girlfriend. So my pillow got really hot and I couldn't fall asleep. That's when I pulled a pillow substitution. It was some tag-team, fresh action.
pillow substitution by juanch June 17, 2010

Tubstitutionalized 

When the dog won't come out of the tub, or runs to it whenever she's afraid or uncomfortable. Situations such as, but not limited to, rain, thunderstorms, high winds, unexpected loud noises, construction, garbage/recycling trucks, doors of port-a-pots closing sharply.
My dog hasn't come out of the tub for more than food or drink in days because it's raining, she must be tubstitutionalized.
Tubstitutionalized by AgilityDiva October 27, 2012

substitution property 

The idea that if a = b, then a may be replaced by b in any mathematical or algebraic expression.
If x = 3, then use 3 instead, its part of the substitution property.