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1.
The sale of items in large quantities. Typically, wholesale is for retailers who wish to purchase items at a lower price to sell them for a higher price. see profits
Upon arriving at the website, Ol' Johny realised that he could not purchase his desired item, as it would require the purchase of other items because the site only accepted "wholesale"
by z@k May 03, 2009
 
2.
a slang term often used in the glenbeigh region. It can take on a variety of different meanings depending on the situation. Most often it means "constantly" or "yes"
"Sure he's at it wholesale!"

"You going out tonight?" "Wholesale!"
by awwbah May 21, 2010
 
3.
something so good, it is like getting it at an exclusive price.
That last tune was so wholesale!
by panic December 04, 2004