Def. 1 (verb): to genetically alter a non-human species in such a way that they achieve a level and style of intelligence approaching that of human beings.
Def. 2 (noun): the process of uplifting a species.
Def. 3 (noun): an uplifed species or individual members of such a species
Bachground: Possibly first coined by David Brin in his series of science fiction books "The Uplift Saga".
Def. 1 - Although they still had decades of work ahead of them, technology had finally progressed to a level where octopi could be uplifted to become functioning members of human society.