When someone puts two thumbs up someones anus along with their penis and preforms anal sex.
You better shut up or i'll give you a Two Thumbs Up Charlie Brown
by Constable Headshot January 16, 2008
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When a guido approaches slowly in his tricked out Honda Civic, speeds up for the 2 seconds it takes to pass you in order to look sweet, then immediately slows down again.
Two Second Speed Up
by CPD2011 April 20, 2011
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Accidental anal entry during sex that causes the female to shoot forward and head butt a third participant
I pulled back too far and rammed it in Jill's ass she jumped fowatd so fast she and Jen caused a two car pile up.
by Deeznuts617 January 16, 2016
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In the traditional sense, if someone is "up to no good", they're doing something bad, or wrong.

WE ARE NOT TRADITIONAL.

We are a collective that defies all odds, a group of individuals, comrades from all walks of life.

Regardless of whether we have different beliefs, careers, experiences or values, we are all Up Two Know Good.

"Up Two" as in two steps ahead, in the lead, striving to win.

"Know Good" as in seeking Knowledge of Self, living the "good life".

We have chosen to commit to knowing better, with intentions of doing better.

We are seeking out the very best in ourselves and in every aspect of our lives.

(Taken from UpTwoKnowGood.com)
What's Good?

Those kids are Up Two Know Good.
by What's Good October 15, 2014
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A pun on the internet meme "Two Girls One Cup" depicting Princesses Peach and Daisy holding a One Up Mushroom.
Ever heard of two girls one cup?

yes and i prefer two girls one up.
by ShadowEan November 4, 2010
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When you hit something with your truck, but another truck hits it too, so you don't have to take the blame.
Melodysgrace pulled the old two truck cover up when he crashed his truck into an awning, but a food truck hit it again.
by Lenny The Meme Master May 5, 2016
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