1. A group/gang of Tweekers as is commonly found with meth addicts
2. a large group of persons who may not necessarily be tweekers but exhibit Tweeker Behavior
1. "There was a twaggle living next door until the cops raided their meth lab!"
2. Do those assholes ever sleep? THey're a f'n' twaggle I swear.
by blagwell October 16, 2009
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The host sat us next to a twaggle of Trumpsters at lunch today so we asked to be moved.
by Str0ud February 27, 2017
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