To throughly own or school someone. A way to measure whether someone has been taken to the house is whether it would be appropriate to inquire of the person in question: "How's your hole?" If asking such a question would indeed be befitting of the situation, then that person has indeed been taken to the house.
A heart-warming children's story to demonstrate the meaning of "take to the house":
Billy's dad told him that he was taking him to Disneyland for the day and told him to close his eyes. After a half hour of driving, his dad instructed him to open his eyes again. Billy realized he was not at Disneyland, but instead back at his house again. His dad then yelled, "Slizzam!!! Got you, sucker! No Disneyland for you, you little bitch!" and started laughing hysterically. Billy then began to cry as his dad taunted him, "Wah wah!!! You little crybaby! I'll give you something to cry about!" Looks like little Billy got taken to the house on that one.

Also:
Fred Weis got taken to the house in the 2000 Olympics when Vince Carter simultaneously dunked over him and teabagged him, shoving his nuts directly into Fred's face.
by Nicholas D November 23, 2007
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Commonly used in sports, to "take it to the house" means to score a point in a big play. The term is almost always used in the context of American football, usually after a player gets a large breakthrough play and takes it all the way to the endzone after a long run.

This term is also applicable in American football when a player catches an interception and runs it all the way for a touchdown (coined as pick six) or when a player returns a field goal kick that was either short or blocked (coined as kick six after the 2013 Auburn-Alabama game).
"And he's gonna take it to the house for the win!"
by Psedoudnym January 4, 2017
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to do it to it; go all out and do it real properlike. real horrorshow.
Hell yeah we're going out tonight; we're gonna take it to the house.
by Marco St. John May 3, 2005
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To go home to take a poop, instead of at work, school, stores, restaurants, etc.
Bill: "Dude, I gotta shit in the worst way!"

Ted: "Then go, dude- Wal Mart's bathrooms aren't that dirty."

Bill: "Screw that bro, I've gotta take it to the house!!"
by J3553 January 16, 2009
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Sexual terminology for take your woman to the house and get your game on
Damn guy, take it to the house.
by HA! September 19, 2003
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What Mason McAlexander says while recieving a blow job.
Mason-Oh yeah take it to the house
Stephanie-Shut the fuck up! I'm only here because you're paying me!
by ADM September 21, 2003
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