to have consumed food in such a large quantity that you feel your stomach is very full, to the point of almost or beyond the point of feeling nauseous.
"I'm so stuffed, I couldn't possibly get another piece of that delicious cake down."
1.to be tired
2.to have eaten so much you became stuffed
3.if someone its being a tool you simply say "get stuffed" instead of get fucked.
1. "i just had a 4 hour long session with my missus im stuffed"
2. "i ate that whole chritmas turkey im stuffed"
3. Tool: hey asshole get the hell of my wife.
You: get stuffed