To unexpectedly -- and spectacularly -- destroy your career in a single act so obviously wrong that having someone tell you "you should know better" would be blatantly redundant
Bob was on track to make regional manager until he spitzered himself
by Chip M. March 11, 2008
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A married, government official, who gets caught administering substantial amounts of money to have sex with a prostitute(s) over the course of many months/years well aware how wrong it is and the consequences.
I hope one day when I become governor of New York I do not become a spitzer, and if I do, I hope I do not have a coach sleezy happen to me.
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A middle-aged man who prefers younger women - and not in a good way.

The opposite of a sleazier style of cougar.

"Can you believe how that old guy tried to hit on my girlfriend? What a spitzer!"

or

"You think she's a cougar? You should see my boss - he's a real spitzer!"

by Treasure Island April 5, 2008
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Someone who advocates against what he is, does, or believes.
Hypocrite
We didn't have naked rituals when I joined the frat like you do now, so don't be a spitzer and stop picking on Richard.
by Bob Caron March 13, 2008
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A prostitution client who insists on condomless sex with a prostitute.
"Kristen was concerned for her personal health, so she had a strict 'no spitzer' policy."
by Hayduke March 12, 2008
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Anal sex with a prostitute without a condom.
The hooker wasn't gonna let me spitzer her unless I tipped her an extra thousand dollars.
by Spitzer12345 March 12, 2008
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A very intelligent and accomplished person who does an extremely stupid thing which ruins his/her career.
My physics professor got caught plagiarizing from a grad student's research paper. What a spitzer!
by UD Reader July 11, 2008
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