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1.
A heavily accented way of saying "sure", pronounced as "shoy".
Shoi, shoi. (Sure, sure).
by tit4tat October 15, 2009
 
2.
Literally, "sure is". Can be used in a variety of context. Used heavily be elderly african-americans who work in industrial shipping settings
Tom- Is the package ready to be shipped?
Tony- Sho is big daddy

Tom- Tony, is there a meeting today?
Tony- Sho is T-Money
by Tom Wage September 03, 2003