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1.
someone who messes up consistently
Your failing, Jimmy?! I swear it, you're gettin to be a screw up.
by Nicole February 16, 2004
307 57
 
2.
1. To fail at something, to do something wrong/incorrectly (sometimes repeatedly). Someone that screws up a lot is called a "screw-up"

2. To describe hurting someone emotionally or physically. Commonly used when threatening the one you want to hurt.
1.
Person 1: "I stayed up late last night to study but I couldn't concentrate that well."
Person 2: "You're gonna screw up that test."

"This is the 5th time in a row I'm getting a bad grade. I'm really screwing up."

"I couldn't stop stuttering when introducing myself to him. I screwed up so badly."

2.
"Oh yeah!? You wanna mess with me, kid!? Ohh, I'm gonna SCREW YOU UP!"

Person 1: "Haha, I totally screwed that kid up, did you see his black eye?"
Person 2: "Yeah, he deserved it!"
by HaltDenMund December 20, 2010
87 59
 
3.
To make a mess of something, to completely ruin something, to make a mistake
Ffs, what a Screw-Up.
"did you see that? what a Screw-Up!"
by FelixB666XD November 08, 2009
17 1
 
4.
Screw up is when you say the wrong name to your bitch while having sex.
uhhh Britney spears, you're so hot - SLAP - My name is Celine dion you stupid motherfucker!
by Kasper Nielsen April 03, 2004
151 306