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1.
to protect someone esle from the attention or criticism due for a particular activity; To help someone in the performance of a task, but not directly assisting in the task.

From American Football where certain players are detailed to prevent the opposing team from tackling the palyer with the ball, by interfering with them.
a:"How am I gonna get these Playboys into the house while mom's there?"
b:"You go round the kitchen door, I'll run interference by showing her the job I did on the lawn"
by D F Stuckey May 12, 2004
61 6
 
2.
originating from football, to attract attention to yourself or throw yourself into harm's way to help out a friend.
your ex just got here - you leave out the back and i'll run interference.
by Erin May 13, 2004
48 7
 
3.
To cause a commotion make a spectacle of one's self or to just generally draw attention to yourself in order to allow someone to do something.
I had my sister run interference with my boyfriend while I got this guy's number
by Chelizsa June 01, 2004
26 14
 
4.
To deflect attention away from someone else.
My buddy and I used to run interference for each other by taking turns playing racquetball with the husband to get him out of the house, so the other one could visit his home to fuck his wife.
by baldyguy December 10, 2011
5 3
 
5.
to provide justification, protection, etc.
The older girl ran interference for their daughter while she set up the prank on their back porch. (example of run interference)
by The Return of Light Joker October 02, 2010
6 9
 
6.
When a person steals something from you and you chase after them in order to stop them.
i ran and interfered his ass
by Will May 12, 2004
2 49