Top Definition
rls
Restless leg syndrome, a sleep disorder
everyone in california has rls.
Babe I got rls again (down boy) can't sleep.
You can get rls from watching too much TV.
Need to call FEMA to help California's get over rls.
by itichie_nocanpo August 10, 2006

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RLS
Real-life shipping, real-life ship

Shipping two (or more) real people.
"I totally RLS my two best friends. They were clearly made for each other."

"Britney Spears and Simon Cowell are my favorite RLS."
by goldiloks October 10, 2012

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rls
- release
- release button
wtf, so many new rls groups in teh interweb!
where's the crack in teh rls?!
by 548q4a541 July 03, 2011

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Stands for

R. Really
L. Long
S. Shaft

A syndrome characterized by having an abnormally long or large penis shaft.
Girl: Why can't you sleep?
Guy: I got the R.L.S. I keep gettin tangled up.
Girl: Youre gettin tangled in your legs from Restless Leg Syndrome?
Guy: Nope.
Girl: ;D
by Longbird May 11, 2011

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rls
A shortened version of the verb and noun raw like sashimi. Used to describe the feeling of wanting a certain version of music immediately.
"If you wanted the latest Eminem album, Id tell you to get online and RLS it"

"I've been RLS-ing all week and my hard disk space is running out"

"Tammy is fast asleep. I think shes all RLS-ed out!"

by Verbia March 25, 2006

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RLS
rapid lesbian sex
Cleen: Hey Rach, you feeling down?
Rachel: yeah
Cleen: how about a little RLS to cheer you up?
Rachel: YeAHHH baby!
by Collie69 January 14, 2009

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RLS
A disease made up so people have yet another excuse to complain. (Bitch Disease)
Joe - Steve, I'm not going to make it to the party tonight, I have RLS....

Steve - What ever homo go have but sects
by teh_architect May 24, 2007

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