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1.
Used at the end of an email when you wish to tell the person "fuck you" in a passive aggressive manner.
Normally:

Thanks,
Chris

Fuck You:

Regards,
Casper
by ccasper July 06, 2010
 
2.
Short for regardless.

No matter what

Despite the influences of the environment

Originated in Kent, WA

Credits to Jory Davis - Man Weekend 2008

Also see: Regardless of the circumstances
greg: aye boy wuh guh
mike: dunno dude, blunts and breezies?
greg: regard
mike: gard
by wachadbros January 19, 2010
 
3.
Short way for saying best regards at the end of an Email
....
Regards
your name / email
by Fernando Cabal June 15, 2007