A filthy whore who has so many STD's that she gets sores, boils, and zits on her vagina, causing her to excrete pus from her genitalia.
Dude, that fuckin whore has a fuckin pustule pussy; see that shit running down her leg?
by Cum%Andrew%Dumpster October 21, 2007
Get the pustule pussy mug.
A single piece of pasta which isn't a noodle I.e. Penne
by Dedraterdater February 14, 2023
Get the Pustule mug.