Can be used to define a number of things. Usally when you are drinking get all fucked up, vomit, and begin to drik again. However it can be used to describe any event that made you puke and you then resumed with even more gusto than before

Drinking heavily until one drink throws you over - puke and rally and you're back in the game. Drinking as if the night is young. Cheers.

Perserverance in the face of gastro-intestingal rejection.