Top Definition
pio
to "play it off"; used to describe instances where someone messes up or makes an ass of themselves and needs some sort of recovery, immediately.
boy: haha, that girl just fell in the dirt!
girl: she needs to pio.

boy: ouch! i just hit my head in the door and everyone saw. i'm a fucking moron!
girl: no worries, pio. it could have happened to anyone.
by Vel J February 06, 2009

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Pio
Slang term for the University of Minnesota's Pioneer Hall in the Superblock. Giving T-hall (Territorial) a run for it's money for being the "Party Dorm."
The guys in Pio third floor North are a bunch of Bro's.
by GoldykillsBucky December 09, 2010

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Pio
Commonly in San Diego. A guy who has mad swagg and pulls girls all day. Someone who also has fresh fits
Woah bro! I thnk hes pullin a Pio!"
by LIl Mack daddy October 20, 2010

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pio
chicken vagina

in some cases may be referred to the noise chickens make when they have sex
Daryl loves her pio.

When Paula screams it's like pio.

They just can't wait to get more pio.
by crazyychickk001 December 05, 2010

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Pio
Pio: (adj, P - oh): Used in reference to, or in association with individuals of a particular caliber of intellect.
"Good god that guy is a Pio!"
by smogellin_johnson October 29, 2011

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Pernounced (P-e-e-u-s) is a very well known word used in situations when someone is being "That guy." Instead of telling them to shut the fuck up, call them a Pios.

Also known as emo bitches or pussies.
Wow, you're such a fucking pios you loser.
by 09wheresTheLine July 24, 2009

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Basically means 'Putting It On'.
Person 1 - "That kid's crying because he fell over".
Person 2 - "P I O"
by twenty4carrot January 29, 2008

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