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1.
A jetstream from Hawaii and Canada that picks up dirt and mixes it with marijuana in a special way that produces powerful weed.
Bob: Ey dude, where'd you get that bud from this weekend?
Tom: Straight from the Pineapple Express man, top of the line shit.
Bob: How much for a dime?
by DR. DEL ONE January 19, 2008
 
2.
The dopest dope I've ever smoked.
Pineapple express is hands down the dopest dope I've ever smoked.
by phuckthepolice-9est August 06, 2008
 
3.
1. This is like if that Blue Oyster shit met that Afghan Kush I had - and they had a baby. And then, meanwhile, that crazy Northern Light stuff I had and the Super Red Espresso Snowflake met and had a baby. And by some miracle, those two babies met and fucked - this would the shit that they birthed.

2. The product of baby fucking.

3. God's vagina
I smoked some Pineapple Express last night. Hands down, dopest dope i ever smoked.
by Jamerz113 May 12, 2009
 
4.
Probably the best and funniest shit ever committed on film by humanity since the dawn of history. Due to August 8, 08.
Dude #1: I can't wait to see Pineapple Express, dude
Dude #2: Why? Seth and Judd are nothing but pothead stoners with bad toilet humor!
Dude #1: *stab*.
by Dude of Life July 10, 2008
 
5.
High Grade medical marijuana grown in Southern California. A hybrid cross created from a forced hemaphrodite OG Kush plant pollenating an AK-47 female. Primarily(75%) Indica wih Sativa undertones. Medium Height. A taste of pine, apple & citrus. THC 16.8%
That Pineapple express was dank!
by MadHatFarmer March 31, 2009
 
6.
1. An extremely potent marijuana that is a cross breed between Pineapple Kush and Train Wreck. The

Dopest Dope ever smoked


2. The best movie ever.
Maaan, that Pineapple Express wrecked me. Good bud.
by TonsofFun327 July 23, 2009
 
7.
When your drug dealer wants to be your friend.
Nah, lets use your guy, my drug dealer is going all pineapple express on me
by newbrains December 05, 2010