In American football, a pick 6 is when an interception is made and returned for a touchdown (i.e., 6 points).
by cajunchick May 1, 2010
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A play in football where the quarterback throws an interception and the defense returns it for a touchdown
God damn it! Chris Turner threw another pick 6!
by nhl_nfl_nba October 24, 2009
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In football, when a defensive player intercepts the ball and takes it all the way back to the other teams en-zone for a touchdown.
Did you see Josh's pick 6 to da crib yesterday?
Yes! It was a game winner!
by Joey Kittel November 10, 2009
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