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From Hebrew

It means someone who is high
Person to high friend: "dude are you patsuts?"

High friend: "haha yeah"
patsuts by White jackdaw August 25, 2018

Pantsuit Death 

The excruciating death of spirit that occurs when a bright and industrious individual must interact with government bureaucrats in order to fulfill an administrative requirement. The termination of goodwill and optimism that occurs when a capable individual must, by necessity, work with administrative bureaucrats.
The expression derives from the word pantsuit, which is the uniform most commonly worn by the mid-level administrators that maintain bureaucracies.
I had to take the mandatory diversity-awareness course this morning; it was total pantsuit death.
Pantsuit Death by frankshoe April 28, 2009

pantsuit 

A person who is being uptight and stiff. Not knowing how to relax oneself.
Stop being a pantsuit, you're stressing me out!
pantsuit by Eastondle May 17, 2012

pantshittingly 

Adjective; can be used to describe how drunk one got the night before.
I got pantshittingly drunk last night and woke up in the morning smelling like shit and shame.
pantshittingly by derebeker June 7, 2011

Pantshitter 

Someone who shit there pants.

As Plural it's pantshitters
Refer to Kski's Song Already Buzzing.
Poo someone shit their pants, he is a pantshitter.

As Plural it's pantshitters
Pantshitter by Mr. Msbehavior January 1, 2020

poopy in my pantsies 

when u go poopy in ur pants
Friend: “Brandon, lets go!”
Brandon: “I just went poopy in my pantsies.”