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1.
According to American Dad, that's when you poop while holding hands.
My friend and I are off to do a number 4.
by mactastic2009 March 16, 2009
109 29
 
2.
when 2 people take a shit at the same time while holding hands!
dude i gota take a number 2 u commin? we can make it a number 4
by gary shackleford March 18, 2009
65 34
 
3.
Slang for heroin. AKA number four heroin. Its etymology refers to the last of a 4-step purification process in which heroin is purified into a white fluffy powder.
Aunt Hazel warned cousin Charley of the dangers of doing number 4.
by J town booga December 24, 2007
49 21
 
4.
Urinating, clearing your bowels and masturbating in the same trip to the washroom. Also referred to as a piss, shit and a wack!
I was supposed to meet K Lo at the party in an hour, but I needed to make time for a number 4 — so I called her and said I'd meet her in 90 minutes.
by Phineas Taylor Barracus December 20, 2004
64 53
 
5.
When two friends defacate at the same time in a public restroom and hold hands under the stall.
James: Hey Steve is that you in the stall next to me?

Steve: Yeah man.

James: Are you taking a number 2?

Steve: You bet. Are you?

James: Yeah we should hold hands and take a number 4.

Steve: Omg Yeah!
by Wannnabe55 May 21, 2009
22 17
 
6.
a picture message that includes the sender's penis
Casey sent Sloan a number 4. She has not texted him back since.
by JP Lubrano February 08, 2011
9 10