Top Definition
male-to-female transsexual
my girlfriend is an mtf.
by neitherday October 31, 2006
10 more definitions
a male to female sex change
by loco weed April 24, 2003
Medical Acronym (usually the ER) for Metabolize To Freedom. Meaning letting a drunk or high person sober up till they can walk out.
pt medically clear. dispo after mtf.
by Ratchet, RN July 21, 2010
More Than Friends. People who are close in nature but are not dating. Also reference fuckbuddies and friends with benefits.
Fred: "Is it just me or are ya'll really close?"
Me: "Yeah but it's nothing serious. We're MTF."
Fred" "MTF??? What the hell?"
Me: "yeah, MTF... you know, more than friends???"
by DrakeVanBuren November 03, 2010
More to follow.

This terminology is often used especially within the military (I.E. if someone gives out a list or set of instructions that are subject to change at any time, they end it with "more to follow").
Tonight, I'm going to hit the hash pipe, borrow my friend's car; then we'll see where the night takes us from there. Mtf..
by acesfilter February 09, 2009
Mother Texting Firetrucker - an expletive phrase created by Winona for her mother Helena in response to her constant use of chatspeak to text, comment on facebook, & other social networks like a teenager despite being 45 years old. It employs the use of the firetruck word in lieu of the more inflammatory word created when one drops the "iretr" from the middle of "firetruck".
Helena: lolz! ur funny! cu l8r, k?

Winona: MTF...
by LakotaGirl May 26, 2012
The abbreviation of, most commonly, mother fuck. When used with an exclamation point instead of a question mark, it becomes an exclamation of amazement, confusion, disbelief, ect.
Guy #1: Dude! I'm going to the hell with u MTF!

Guy #2: Motherfuck, man... i dont want to go to hell.
by Rayraylee July 10, 2010

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