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1.
Rich peoples medicine or more accurately referred to on the street as MDMA that is smuggled into the United States by Hasidic Jews.
Vickee: I really wish I knew where to get some Molly from for tonight.

Maddy:Fuck that shit... Yosef's got the connect on that bomb ass Mazel straight from Amsterdam!
by MaCoII June 11, 2011
35 6
 
2.
A shortened way of saying "mazel tov," the Hebrew "Congratulations." It means the same thing.
Mazels on your promotion!
by Office shiksa April 28, 2009
9 1