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1.
Someone who is crazy, or acting crazily.
"Look how recklessly that man is driving. (he is a) madbrain"
by bananamilkshakefiend October 15, 2009

Words related to madbrain

madhead mental mentalist spackie spaz
 
2.
Mad Brains is a synonym for the incidence of receiving a very good blow job.
Man, that girl gave me mad brains last night.
by pba24899 February 20, 2010