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genetic lifeform and disc operating system 

The acronymic meaning of GLaDOS.
Aperture Laboratories Genetic Lifeform and Disc Operating System, or GLaDOS, filled the room with neurotoxins.

Ultimate lifeform 

A living creature that's reacted perfection.
Dude1: have you seen the ultimate lifeform
Dude2: shadow the hedgehog or kars?
Dude:1 ummmmmm

detecting multiple leviathan class lifeforms in the region. Are you certain whatever you’re doing is worth it? 

Following this PDA warning there are two scenarios.

A: you ignore it and shit your pants to a reaper leviathan seconds later.
B: You turn around and your pants get to live another day
PDA: “Detecting multiple leviathan class lifeforms in the region. Are you certain whatever you’re doing is worth it?”

You: “I can’t possibly imagine what could go wro-AHHHHH,SH** YOU CU*T GO F*** YOURSELF, NO NO NO NO NO JESUS.”

Your seamoth: *Dies*
Your pants: *Turn brown*
A hole in your monitor: *Appears*

The Ultimate Fury Based Lifeform 

TUFBL is a being created after combining ANGER and RAGE. The anger is referred to as: “Angrygram” and the rage is referred to as “Bugatti Blasta”.
The Ultimate Fury Based Lifeform is full of rage!

estrogen-based lifeform 

Susan is an estrogen-based lifeform.

Ultimate Lifeform 

Altmer is the definition of ultimate lifeform
Ultimate Lifeform by Saitama 777 September 11, 2021