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Literally means, "Okay, thanks, bye" Usually said to be a bit more sarcastic and rude when trying to make a point. Used to end a conversation/point quickly.
"You're so stupid, don't ever talk to me again, kthxbi."
kthxbi by priceisright August 29, 2005
Related Words
Literally "Okay, thanks, bye". Commonly used when short words and phrases are needed, as in when chatting and texting. Can also be used to quickly end a conversation, usually in a rude fashion.
Jane: "Hai John! Sup?"

John: "Nm, gtg, kthxbai."

or

Jane: "Hey John, why won't you talk to me?"

John: "Because. kthxbai."
kthxbai by avengergirl May 14, 2010
I understand. Your help in this matter has been greatly appreciated. However, with much regret and much haste, I must be departing from our conversation.
newb2342: da partiez @ 4, b there!!1
lolz3r: kthxbi!!!!11
kthxbi by i made this box June 19, 2003
Word of the Day on January 19, 2009
Could you please boot that n00b from the server? kthxbai
kthxbai by squidblaine May 9, 2004
this means ok thanks bye

k = ok
thx = thanks
bi = bye
'ill drop round yours later to drop round your dvd, cya'
'kthxbi'
kthxbi by Dave Gordon July 7, 2004

kthxbyaaah! 

Okay, thanks, byaaah! (byaaah, from Dave Chapelle's Howard Dean skit)
Generous Person: Here's a thingy. Enjoy it while it's fresh.
Howard Dean: Kthxbyaaah!
kthxbyaaah! by Chris G Selector August 21, 2006