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A hug (or cuddle). The original Dutch word 'knuffel' was deemed to be English sounding enough to be fully incorporated. Knuffle sounds the same and means the same.
I gave janet a big knuffle during the full moon.
by StartRunning March 30, 2010
Definition : knuffles = cuddles

background : WINMX... /action knuffles (someone).
Sam knuffles Lei all night long.
by yup September 05, 2004