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irritation 

the state of feeling annoyed, impatient, or slightly angry
P1: he was such a irritation pretending to care.
P2: you don't care either!

P1 : oh ya forgot LOL
irritation by ... Zjdbckdnznsjd September 10, 2019

Irritation Domination 

The feeling one gets when a situation suddenly goes wrong causing major stress.
Eric suffered severe irritation domination when he realized his zipper was down, exposing his shortcomings.
Irritation Domination by Diggler October 20, 2016

Irritation Of The Anus 

A painful symptom after you have expelled flaming lava liquid shit out of your asshole
"God.. My diarrhea gave me irritation of the anus... and it hurts like mega hell."

Irritation Politics 

It started in Hollywood ,you get famous by trying to irritate people.
Then it went into politics. You irritate people to get votes.
The religious irritate the non-religious , liberals irritate conservatives.
No race ,religion ,belief or anything is off limits. Nobody has the right to not be insulted.
When Steve Bannon wrangles and organizes bigots for Don Trump ,that is irritation politics at work.
Irritation Politics by anonymous August 11, 2022

Advert Irritation

Advert irritation is a symptom of Counterproductive Advertising and is what happens when an advertisement is incorrectly targeted or when an advert is seen too frequently. There are two possible reasons why this happens:

1 The advertiser believes that screening the advert at every opportunity will increase sales; research by In Skin Media and RAPP Media shows that it just annoys people and makes them less likely to buy.
2 The belief that an advert made for the United States’ will be successful in the United Kingdom. The reasoning being that because UK customers understand the language in which the advert is made, they’ll identify with the product and everything else will fall into place. The advert may be well presented, but the customers are irritated by it either because the concept is alien or the presenter is unfamiliar.
The worst possible scenario is incorrect targeting and too frequent exposure. This happened with an advert for Lenor fabric softener screened in the UK during 2015. Originally made for the US market, it featured a minor American actress, Amy Sidaris, who was unknown in the UK; Sidaris’ manner was very much “in your face” which didn’t go down well with the more reserved UK customer base. A typical reaction of people watching was “who does this blonde bimbo with the big bristols and the weird accent think she is telling me how to do my washing?” This irritated reaction to the advert means that the customer is less likely to buy the product.
An incorrectly targeted advert, or one shown too frequently, results in advert irritation and lost sales.

Pachelbel's Extreme Irritation 

Another name for the Canon in D, thusly called for being outrageously played out, and because of all the people who call it their favorite classical piece because it's the only one they know. Used especially among cellists.
Not ANOTHER request for Pachelbel's Extreme Irritation! If we have to play it one more time I'm going to gauge my eye out with this bow I hold in my hand.