Top Definition
If you go to any medical-scientific dictionary you will find hypophrenia means "mentally retarded."

However, a lot of dumb 12 year olds on tumblr think it means "a vague feeling of sadness, seemingly without cause ." causing them to write sad little posts and desperate asks on yahoo answers about their hypophrenia and how to get rid of it
Maybe they really do have hypophrenia
by jaeme May 13, 2011
a vague feeling of sadness, seemingly without cause .
## - you seem kind of depressed today , what's wrong ?
$$ - nothing i guess, i'm not even sure to be honest .
## - sounds like hypophrenia .
by baileystpierre August 10, 2010

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