When 2 people kiss and/or fuck.
I agree, it depends on your region.
'I hooked up with your sister'
by Diego November 13, 2003
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a way to get something you want. either thru someone or something.
yo, i dont need to do hw cuz i got the hook up
by da madd scientist October 3, 2003
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Guy A:"Did you hook up with the guys last night?"
Guy B:"Yeah. Guy C hooked us up."
Guy A: "Was Girl 1 there? Y'all should hook up."
Guy B: "She hooked up with me after. We, like, hooked up."
Guy A: "So...did you hook up?"
Guy B: "No."

An actual conversation, heard on the Chicago CTA.
by Scrivv July 28, 2009
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1. recieved a good or service as a favor
2. to make out with someone
3. to have sex with someone
1. Jerry gave me the hook up with those backstage passes.
2. Sandra and I hooked up last night and her adams apple was kinda big
3. Hooking up with Derick last night was the biggest mistake in my life.
by Doctor Crayon December 31, 2004
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1. In middle school: holding hands and hugging
2. In high school: making out, fondling, handjobs and blowjobs
3. In college: drunken one night stands
4. Beyond college: wild sex
1. Sean and Jennifer hooked up after school yesterday.
Middle school girls: "oooooh!"

2. Sean and Jennifer hooked up after prom.
High school friends: "tell me more about this!"

3. Sean and Jennifer hooked up during the wild frat party.
College broskis: "yeaah, good for you, man!"

4. Sean and Jennifer hooked up after they got wasted at the bar.
Anyone: "casual sex? whatever, happens all the time."

And that's how people hook up.
by Grandma Maxie July 19, 2011
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verb: to engage in any type of sexual activity.
noun: 1. purposely ambiguous, equivocal word to describe almost any sexual action. usually used to exaggerate or minimize what exactly happened. a hook-up can range from a make-out session to full out sex.
2. person you hook up with
a: "so what did you guys do last night."
b: "welll, you know...we hooked up."
a: "come on! that could mean anything. give me details!
by nerm November 7, 2004
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Nobody knows exactly, can be anything from holding hands to having anal sex. Pretty sure it drives most normal people insane
Bro: yo did you hear, hoe from our school hooked up jock?
Me: No. What did they do?
Bro: They hooked up
Me: Okay but bro, like, what the FUCK DID THEY DO?
Bro: How the hell should i know, i just heard they hooked up! fuck

(and now i searched for what it means on UrbanDictionary.com and still couldn't find an answer)
by Bob Marusi October 10, 2011
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