Top Definition
epic fail when trying to spell homie
loser: yo whatsup holmie?
reallycoolkid: what?! 'holmie'?! no... epic fail.
by anita morehead March 07, 2009

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Holmes or dog or G but Holmie with the accent
Sup my holmie What you doing holmie dawg G
by Fogat January 28, 2008

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An avid Sherlock fan (BBC Television Series based on the Sherlock Holmes series by Arthur Conan Doyle)
Friend 1: "OMG, Sherlock & Watson should SO get together!"
Friend 2: " *eyeroll* You are such a Holmie."
by Penguinsdontfly February 29, 2012

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Friend of a friend. Little holmes. Your Homeboys Lady. A Clown that will hit you with a stuffed sock. i.e. Holmie don't play that.
What up with little Holmie.
by edwarde April 28, 2006

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