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1.
a girl who is mega ho to the point where you cant even say ho correctly. the word can also be used to unify and bond friends when talking about how slutty a girl is as she walks by: one friend begins by saying "H to the.." and his friend responds "...izo!" noting that he also agrees with his friends initial judgement that the girl is clearly a skank.
"H to the..." "...izo!"
"damn that girl is a hizo! her skanky ass loose pussy is open for everyone at all times!"
by bevi September 13, 2006
 
2.
The ghettolized word of hoes.
Let us bang all these hizos in the parking lot.
by somemoron May 01, 2005