Top Definition
1. The grasping of hands by two people, as in greeting or leave-taking.
2. Computer Science. An exchange of signals between two devices when communications begin in order to ensure synchronization.
Jerds gives Spengler The Handshake™.
by Anonymous March 19, 2003

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a casual fuck.
"Honey, don't be mad! It was just a handshake!"
by me May 31, 2004

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The most sacred form of sealing a deal.
A mutual agreement amongst two people to abide by clear and agreed upon terms.
Anybody who would break these terms is a gigantic faggot, see welcher
Men get sued over contracts, but men get killed over handshakes.
by ScrubbyNinja July 10, 2008

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slang for jerking off
march 19th is national handshaking day.

or

have you had your handshake today?
by Billy Bichititimen January 27, 2005

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When a girl or boy tosses a boy off.
Oh my god, that sket hand shaked James last night!

Want a handshake, ;)
by Randomise November 01, 2006

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Handshake - A type of currency used in the night life to pay for undisclosed services. Handshakes come in different denominations and sizes depending on the service and the hand.
Hi sir, I need to skip line. How much would it cost me. "It will be 2 handshakes".
by HMarz818 June 14, 2016

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a medieval high five
Sir Thomas, mounted on his black stallion, gave a handshake to Sir Jamal as they passed one another on the street. "Wut up dawg," responded Sir Jamal.
by Butzo November 15, 2006

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