A more extreme version of "yikes".
Originates from the season 4 episode "Fast Times at Buddy Cianci Jr. High" of Family Guy.
Fish 1: You know what I hate? A guy in a blue suit.
Fish 2: Geaux!
Fish 3: Ssssss, there's one right behind me, isn't there?
Guy: I'm not sure, but I think I might be gay.