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The situation you are in if your dropship crashes and leaves you stranded on a planet full of nasty extra terrestrials.
I guess this is it, man, I guess we're pretty fucked, game over, man, game over!
by Zalis August 05, 2004
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2
A sure sign that the game just kicked your ass...
I love the game over music for Final Fantasy 7, its just so... sad!
by Rimpala January 26, 2007
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3
when you get married
When he got married, it was game over
by Bryan Pend October 04, 2007
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4
The alternative to You Are Dead! in games that are not Resident Evil
Game Announcer Voice:Game Over

Gamer:Damn i died again

or

Screen Reads: You Are Dead!(in Blood)

Gamer:(screaming) I know damnit
by Chris Duett November 06, 2007
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5
a situation has ended unsuccessfully
If he gets away, it's game over for the credibility of the police chief.
by The Return of Light Joker January 29, 2009
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6
1) Saying that you have the situation in the palm of your hand.
2) When something happens that causes you to give up.
I'm going to the movies in my new APC's and a white v-neck. It's game over duude.

I was talking to this girl and I found out she has a boyfriend. It's game over.
by lightjak2210 September 02, 2010
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7
when u have lost the game usally runing out of lives.
last guy danm i died
GAME OVER
by bob December 08, 2003
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