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1. four
To be in agreement with someone. It can be used in place of the word "Yes". A short version of 10-4. Can be used by raising your four fingers at someone.
(John) Lets get out of this place and grab a few brews. (Tibbs) "Four"
by Steve Mogavero Sep 21, 2005 add a video
2. Four
Refering to the making, pouring, or drinking of "Syrup", which is a mix of pop and promethazine with codeiene. "Syrup" induces a very slow paced "high" such as the movements of a turtle. "Syrup" may be refered to as "Purple Drank" or "Sizzurp" which is a mix of pop, promethazine with codeiene, and crushed up oxycottons. To recap, if someone says pour me a four, well than you know what they mean.
Just listen to Lil Waynes's "Me and My Drank", that is all an example of Four.
3. Four
Four meaning the alcoholic beverage Four Loko.
Ayye I'm going to get a red Four and get wasted.
4. Four
A more proper way of calling a man or women a "hoe" "whore" or "douche".
Me: You know that new kid Luke?
Angel: Yeah, I heard he's a real four.
5. Four
Meaning STD (a four) or someone having an STD, mainly females living in the US age group 15 to 19. This word came the statistic on CNN stating "1 out of 4 girls in United States American ages 15 to 19 do now have an STD, aware or not"
Dude 1 "Hey man you heard about the new girl, pretty hot?"
Dude 2 "Yeah I've seen that fine girl!"
Dude 1 "Well are you goin'a tap that or what?"
Dude 2 "Man if she ain't a virgin she a 4 in my book."
Girl "No, I've had sex before."
Dude 1&2 "Four!"
6. four
Numeric rank referring to anal sex. Based on 1-5 ranking of sex acts, where 5 is the most intimate.
Karen and I did number four last night. Luckily, as it is not number five, we can still be just friends.
7. four
The first number I could find that hasn't been defined here. There are some crazy-ass definitions for one, two and three I can tell you!

Four is the number after three and before five.
Extend all the digits on a hand - now un-extend your thumb. You are now holding up four fingers.
by Detrius521 Feb 27, 2005 add a video
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