When your boyfriend becomes the man he normally is and turns into a boy, guy or dude. This comes at random times of the month. He turns from being the awesome boyfriend to just sucky.

May be similar or related to, but not dictated to male period, or male pre-menstrual syndrome
girl 1: "I think your boyfriend is being sucky right now."
girl 2: "Yeah totally, he's suffering from dude syndrome."
by vysknight December 3, 2010
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The classic syndrome exhibited by those who got beat up, stabbed or shot, and dont want to admit they know who did it. usually by some wrong-doing over drugs or money owed.
dr smith: do you know what happened tonite?

Billy Bob: YA! i was standing on my porch, minding my own business, smoking a cigarette, and "some dude" came along and shot me!

dr smith: did you see this person?

billy bob: nope. it was just some dude.

i.e. some dude syndrome
by princessandrea1219 October 23, 2008
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When a guy doesn't want a girl he has intercourse with or had relations with to talk to anyone else. He will get mad, name calling. Threatening, and easily pissed off at you.
He called you a whore and blocked you Shelly. What the hell does he have "dude selfish syndrome?"
by Shelly Smith January 18, 2017
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When a guy over reacts to a situation that is triggered by a female , loved one , family member. They will see’s red , they would become uncontrollable, no one is safe , jumps to conclusions ( creating scenarios that haven’t happened or potentially happened ) with or with out evidence. Could potentially lead to breaking stuff , showing up places unwarranted , major freaking out , lots of cursing , yelling , long detailed text , lots of voicemails . Essentially going off the deep end .
Gregg found out his girl was texting another guy . Gregg got dude brain syndrome and lost his mind and was creating scenarios in his head and freaking out about anything and everything on her.
by Antics23 March 31, 2023
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