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down’s syndrome 

some of the most amazing people on the planet who are actually extremely intelligent (coz sum of y’all clearly aren’t, throwing shade) and hilarious and beautiful and wonderful human beings. take it from me my sister has it. no it’s not a fucking disease, nothing reduces or amplifies it, you can’t catch it (wtf), people with it don’t suffer, and they’re something funny cute and awesome! so for all y’all insulting people by calling them down’s syndrome, a) find a better insult, b) get a fucking life, c) google it before you use it to be mean and d) think about how other people who know people with down’s syndrome actually feel about you using language like that?!
see that girl over there, she has down’s syndrome, look how happy she is. she looks like so much fun
down’s syndrome by belladanke November 13, 2018

down's syndrome 

Even god finds them funny.
Down's syndrome kid: "Help me, my eyes are r8 small but ma head's pure massive"
Guy watching: "Hahaha oh my god you should be put down."
down's syndrome by sdw298 May 5, 2008

down's symdrome 

down's symdrome:A condition resulting from a chromosomal abnormality characterized by mental retardation and such physical signs as slanted eyes, flattened facial features, short status and tendency toward obesity. this is down's symdrome .
you are a fuckin' mongo!
you got down's symdrome or summit?
down's symdrome by nikki101 June 23, 2006

Internet's Down Syndrome 

A temporary condition brought on by the lack of internet connectivity and characterized by irritability, fidgeting, lack of focus, a general feeling of helplessness and occasionally exercise.
Steve: What's up with the glazed look on Meredith's face?

Brad: Well, she likes to start her day reading Perez but we have no connectivity and slipped into an acute case of Internet's Down Syndrome.

Double Down's Syndrome

A sickness developed while playing Blackjack that causes you to risk all your chips constantly from doubling down.
Jim lost all of his money at the casino yesterday after getting a case of Double Down's Syndrome.

Lay down some G's 

Shahbaz's phrase for putting thousands of pounds towards something.
Guy: I went to a club on Saturday and got a table...
Other Guy: Bet you had to lay down some G's....