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de madre 

Spanish, literally means "from mother" but it actually means unbelievably frustrating, not cool, bad.
Ex1:

Person 1: "How the hell did that happen?!?"
Person 2: "I know, I can't believe it..."
Person 1: " that was de madre"

Ex2:
Person 1: "This game is so hard!!"
Person 2: "This game is de madre"

Ex3:

Person 1: "What?!, you failed art class?"
Person 2: "Yeah.."
Person 1: You are de madre...."
de madre by js1212000 August 23, 2011
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Esta de Madre 

La cosa esta de madre

Concha de tu madre 

Sud-American word used as an insult. The literal translation is : "Your mother's sea shell".

This word makes direct reference to the female reproductive organs and it is considered one of the biggest insults in countries like : Chile, Argentina, Peru and Bolivia.

English alike : Motherfucker.

"¡Déjate de gueviar concha de tu madre!"

Translation : "Fuck off you motherfucker!"
Concha de tu madre by Alfacentauro January 18, 2007

de puta madre 

Southern-spain slang for something that awesome.
1:!...y despues ganamos un million de dolares!

2: De puta madre, tio!

Yo cago en la leche de tu madre 

I think this is a misquote, it should be 'Me cago en la leche que mamaste' which means "I shit in the milk that you suckled from your mother's breast"
Lovely expression, isn't it? (used widely as 'Me cago en la leche')
The above I have never heard, and anyway this is an English slang dictionary not an Eng - Span one.
Spanish speaker one: Acabo de romper tus gafas (I've just broken your glasses).
Spanish speaker two: Me cago en la leche que mamaste, cabróncete de mierda. (I shit in the milk you suckled from your mother's breast you shitty/fuckin'little bastard.

linda de su madre 

a phrase used to express affection when someone does something nice for another person such as giving gifts or an act of kindness.
Person 1: “Christine brought gifts to all the children in the hospital this year.

Person 2: “Aww, linda de su madre”

It can also be translated as “ God bless her heart”.

Yo cago en la leche de tu madre 

Juan, yo cago en la leche de tu madre.