Top Definition
Spanish, literally means "from mother" but it actually means unbelievably frustrating, not cool, bad.
Ex1:

Person 1: "How the hell did that happen?!?"
Person 2: "I know, I can't believe it..."
Person 1: " that was de madre"

Ex2:
Person 1: "This game is so hard!!"
Person 2: "This game is de madre"

Ex3:

Person 1: "What?!, you failed art class?"
Person 2: "Yeah.."
Person 1: You are de madre...."
by js1212000 August 19, 2011

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