Top Definition
The mixture of male semen and female vaginal fluid left on the sheets after unprotected intercourse.
After we finished and I rolled over she bitched about having to lay in the cumbination.
by webster2.0 May 17, 2011
The combination of sexual activities that "turn you on" or are key to a successful ejaculation.
Cristal: "babe what is your cumbination"
Jackson: "I need tits, lube and soft hands"
by Cjak September 19, 2015

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