a horse named Charlie, had his leg spazz out, so every time someones leg spazzed people called it a Charlie Horse. Charlie was the laughing stock so he became a rogue horse.
Rob Horse: "Woh Sarah your leg is spazzing out like crazy!"
Sarah Horse: Guess I've got a Charlie Horse."
by awesome-satay March 11, 2011
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When you punch someone in the thigh pretty hard.
Dude, I gave Mark a wicked huge charlie horse on the bus yesterday and he had to crawl home.
by JamsKo May 4, 2007
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Shotgun a beer with bong bowl piece in top. Light a bowl and it will fill the can with smoke as you drink. When you finish the beer take in the hit.
Oh bonkers, he just passed out after taking a charlie horse.
by RustyDogYo June 10, 2009
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When you say "YA YEET" and bust up your calf
*Jumps in the air*

"YA YEET"

* gets Charlie horse*

"AAAAAAAAH MY CALF FOG HELP ME I GOT A FUCKING CHARLIE HORSE"
by CucciEater142 January 1, 2019
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The deadly concoction of heroin mixed with cocaine in a n injectable form.
"They've been shooting back Charlie Horse all afternoon."
by Joel123 June 18, 2008
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When a male's balls tighten ,and he ejaculates out of his asshole.
Bro I was in the bathroom......and I did a reverse Charlie Horse -_-

My nuts hurt cuz of that reverse Charlie Horse >.<
by Timken April 12, 2013
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