The effect of one thing happening, only for other things, usually negative, to happen because of it.
Person 1: The baby woke up last night, so I lost sleep, so I was less productive, so I didn't get my project done, so my grade is shit, so I can't go to the concert tonight.
Person 2: Aw shit, you got hit by a Chain Reaction.
Person 2: Aw shit, you got hit by a Chain Reaction.
by In My Defense... September 28, 2018
by dbrow May 6, 2007
"chain reaction, reaction time, time flies"
by Jennaaaaaaa August 8, 2007
when, in the event of basketball, one is crossed over so badly, that it makes the defending team crumble one by one, or in a chain reaction, domino effect.
by Whopper G May 9, 2005
When three or more Asian drivers rear-end each other in a domino-effect fashion, potentially resulting in multiple accidents, multiple traffic tickets, and a major traffic holdup.
When I was driving home from work and passed by an Asian neighborhood, I got caught in a Chinese chain reaction, and the front and rear chassis of my car got totaled.
by Terminus_Est May 1, 2015