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1.
The chemical in chili peppers that makes them "hot." Actually a mild irritant.
"How many times more capsaicin does a habañero have than a jalapeño?"
by Qit January 21, 2004
 
2.
Hot sauce
CLuck-U Chicken's famous 911 sauce it made of pure capsaicin.
by Iceet December 29, 2003