A sub-human college student who doesn't know personal boundaries, and will only communicate with you if you are talking to someone else. Who's persistent in obtaining useless knowledge about nothing to feel like something. Also consumes parts of his body.
Brandon: Wow Busey today was being a total buzzkill
Dan: why? was he eating his skin again?!
Brandon: You fucking know it!
by JudgeJudyFan February 16, 2010
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noun - The lesser, crappier, or worse version of two similar people/ideas/objects. Originating from the idea that Gary Busey is a poor man's Nick Nolte.

adjective: Buse; referring to the Busey-ness of something.
Skeet Ulrich is the "Busey" of Johnny Depp.
Dolph Lundgren is the "Busey" of Arnold Schwartzenegger.
Pepsi is the "Busey" of Coke.
WNBA is so "Buse"
by Chris Grant & Sean Haynes October 19, 2004
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feeling or becoming overly aggressive in situations that don't call for it.

exhibiting anger, rage, or incomprehensible behavior.
Look there goes Walter again, he just punch out his window. He's going Busey.

Dude, after you got a all drunk you went all dark and Busey.
by bolo1g2 June 7, 2009
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Adjective
Something insane, incomprehensible, potentially dangerous, not thought out, or overall shady yet completely genius, well thought of, and unforgettable.
Ken: What the hell man? That plan of yours was a real Busey. I can't believe were not in jail... or dead!
by Ken Steckal November 24, 2007
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Something said in place of a curse word or used at any time to break the silence.

First seen on an episode of Venture Bros; said by Brock out of frustration.
When Niki hit her funny bone on the counter, she yelled out, "Ahhh... Busey!"

by E-Rock and ya don't stop October 29, 2008
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When an individual is nasally congested, and they must breathe only through their mouth while they sleep, much like the regular breathing habits of Gary Busey.
"Man, I'm stuffed up, and I Buseyed all night, so now my throat is sore and I'm all dried out."
by Fathawgimus December 15, 2017
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The nether region of a woman with a large vagina and pubic bone resulting in a bulbous mound. i.e. A "clump" of epic proportions.
Look at that bikini on Mary. Nothing can hide her busey!
by Nitz_Ritz June 25, 2009
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